A simple spectrophotometric method for the determination of tetracycline and doxycycline in pharmaceutical formulations using chloramine-T

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A Simple Spectrophotometric Method for the Determination of Tetracycline and Doxycycline in Pharmaceutical Formulations Using Chloramine-t

A simple, rapid, accurate and inexpensive spectrophotometric method for the determination of tetracycline and doxycycline has been developed. The method is based on the reaction between these drugs and chloramine-T in alkaline medium producing red color products with absorbance maximum at the ë = 535 and 525 nm for the tetracycline and doxycycline, respectively. The best conditions for the reac...

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ژورنال

عنوان ژورنال: Eclética Química

سال: 2010

ISSN: 0100-4670

DOI: 10.1590/s0100-46702010000400018